ESPE Yearbook of Paediatric Endocrinology

Diabetes Care 2018;41:1696–1706.doi: 10.2337/dc18-0244URL http://www.ncbi.nlm.nih.gov/pubmed/29941497Summary: In a case control study, age-related differences were compared between youth and adults with impaired glucose tolerance (IGT) or recently diagnosed diabetes. Youth had lower insulin sensitivity, hyperresponsive &#9...

Diabetes Care 2018;41:1717–1725.DOI: 10.2337/dc18-0787http://www.ncbi.nlm.nih.gov/pubmed/29941500Summary: In a randomized, open label clinical trial of 91 adolescents with IGT or new onset T2DM, one-year early interventions with long-acting insulin followed by metformin, or with metformin alone failed to prevent dete...